• Sulfur transfer reagent Indanone and its analogues are usefu

  2025-02-21

  

  1-Indanone and its analogues are useful intermediates for the synthesis of compounds some of which have applications as pharmaceuticals, especially as analgesic and antihypertensive as well as tobacco flavoring agents. Indanones are commonly used as starting agent for the synthesis of ninhydrin whic

• SB-205384 chemical br Results br Discussion Our finding

  2025-02-21

  

  Results Discussion Our finding that AXL overexpression is significantly associated with poor survival in patients with high-grade serous OC is consistent with previous reports indicating that AXL regulates tumor growth in some cancers, as well as reports showing that AXL activity is involved i

• Stroke also known as a

  2025-02-21

  

  Stroke, also known as a cerebrovascular accident or Poly(A) selection beads attack, is one of the leading causes of death and disability worldwide (Haley et al., 2017; Hankey, 2017; Lie et al., 2017). According to the data released by the World Health Organization (WHO), stroke occurs every 5 s wor

• An alternative more rarely used electron microscopy based

  2025-02-21

  

  An alternative, more rarely used, electron microscopy-based approach exploits labeling of phagosomes with DAMP (3-(2,4-dinitroanilino)-30-amino-N-methyldipropylamine). DAMP is a weakly basic compound which is membrane-impermeable once it has been protonated. This way, DAMPH+ accumulates in acidic in

• Acl converts cytosolic citrate CoA and ATP into acetyl CoA

  2025-02-21

  

  Acl converts cytosolic citrate, CoA and ATP into acetyl-CoA, ADP+Pi and oxaloacetate (Fig. 1). This cytosolic enzyme is present in few Prokaryotes and in all Eukaryotes, but not in non-oleaginous yeasts [14]. Thus, this enzyme was presumed to be essential for FA synthesis [1], [13], [15]. In most mi

• ASK has been identified as an ASK

  2025-02-21

  

  ASK2 has been identified as an ASK1 binding protein (Wang et al., 1998). ASK1 supports the stability and active configuration of ASK2 in the heteromeric complex, while ASK2 has been found to activate ASK1 by direct phosphorylation (Takeda et al., 2007). Unlike ASK1, which is ubiquitously expressed i

• The use of FTAI can overcome the negative impact of

  2025-02-21

  

  The use of FTAI can overcome the negative impact of low estrus detection efficiency, but implies effective synchrony of luteal function as well as synchronous growth and ovulation of a viable BMP-2 recombinant protein follicle. Pregnancy rates obtained with FTAI may be comparable or better than thos

• Apelin is involved in various physiological

  2025-02-21

  

  Apelin is involved in various physiological functions, including NSC228155 receptor contraction (Ashley et al., 2005), vasodilatation (Jia et al., 2007), feeding control (Valle et al., 2008), and metabolic homeostasis (Higuchi et al., 2007, Dray et al., 2008, Attane et al., 2010). Its plasma level i

• br Materials and methods br Results br Discussion

  2025-02-21

  

  Materials and methods Results Discussion In this study, the orphan receptor GPR25 was cloned from several representative vertebrate species including zebrafish. Although the overall amino R-848 sequence identity among these species is not high (38–52%), our synteny analysis clearly indicat

• Tetracyclines constitute one of the most important antibioti

  2025-02-21

  

  Tetracyclines constitute one of the most important antibiotic groups used as veterinary and human medicine and as feed additives in the agricultural sector (Li et al., 2011a, Simon, 2005). Annual worldwide production of tetracyclines is estimated to be in the thousands of tons (Michalova et al., 200

• br Introduction Heart failure HF is a

  2025-02-21

  

  Introduction Heart failure (HF) is a chronically progressive disease and one of the most important causes of morbidity and mortality worldwide despite recent improvements in its treatment [1], [2], [3]. The mortality and morbidity benefits of angiotensin converting enzyme inhibitor (ACEI) are wel

• Perforation of the surface membrane however is not the only

  2025-02-21

  

  Perforation of the surface membrane, however, is not the only mechanism of calcium dysregulation by Aβ at the presynaptic terminals. When in excess, both monomers and oligomers modulate biophysical properties of voltage-activated calcium AS-703026 as well as calcium release from the endoplasmic ret

• br Acknowledgments br Introduction Amyloid deposit

  2025-02-21

  

  Acknowledgments Introduction Amyloid deposit formation is defined by the aggregation of β-sheeted forms of proteins that appear as starch-like amorphous material [1], [2]. Using a Kongo red stain, amyloids show birefringence behavior and an apple-green to reddish multicolor emission. Extracere

• br Material and methods br Results

  2025-02-21

  

  Material and methods Results Discussion Nimodipine administration inhibited the level of AMP-activated protein kinase (AMPK) phosphorylation, a sensor of cellular energy status that directs metabolic psora to support cellular growth and survival. CCH influences the oxygen and glucose suppl

• The role of the adaptive immune response

  2025-02-20

  

  The role of the adaptive immune response in AD is not fully understood and previous studies are controversial. In this context, serum levels of T and B lymphocytes were found to be reduced in AD patients, suggesting a decline of the immune response during the course of the disease (Richartz-Salzburg

16245 records 8/1083 page Previous Next First page 上5页 678910 下5页 Last page