• There have been a few studies investigating

  2022-06-02

  

  There have been a few studies investigating the effects of histamine on mast cells but the majority of these has been on rodent and cultured mast cells (Hofstra et al., 2003, Lippert et al., 2004, Jemima et al., 2014). How representative these systems are of primary human cells is a moot point since

• Yap and Taz may regulate epicardial cell

  2022-06-02

  

  Yap and Taz may regulate epicardial cell proliferation, EMT, and fate determination via multiple mechanisms. In this study, we provide evidence that Yap/Taz function in part by directly modulating Tbx18 and Wt1 expression. Members of the T-box family of transcription factors regulate a variety of de

• br Introduction Circulating tumor cells

  2022-06-02

  

  Introduction Circulating tumor 6258 sale (CTCs) are cancer cells that have invaded blood vessels or lymphatics and are carried around the body by the blood. CTCs constitute potential seeds for metastasis because they can reach and implant into distant organs. The clinical importance of CTCs was

• Bezafibrate br Hedgehog in chronic liver disease The liver r

  2022-06-02

  

  Hedgehog in chronic liver disease The liver responds to different chronic insults with a highly conserved wound healing response during which different cell types must communicate to reconstruct fully functional, healthy liver parenchyma. The inter-cellular dialogue that orchestrates effective li

• br Introduction Chronic hepatitis C CHC caused by hepatitis

  2022-06-02

  

  Introduction Chronic hepatitis C (CHC) caused by hepatitis C virus (HCV) infection affects approximately 170 million individuals worldwide [1]. HCV and human immunodeficiency virus (HIV) have similar routes of transmission, including blood-to-blood contact, sharing of injection equipment, and sex

• One important aspect about GSK inhibitors is their effect on

  2022-06-02

  

  One important aspect about GSK-3 inhibitors is their effect on pluripotency of 11e [4]. Many GSK-3 inhibitors are ATP-competitive and suppress both GSK-3alpha and GSK-3beta [476]. BIO was shown to suppress GSK-3 activity and promote Wnt/beta-catenin signaling. This combination of events preserved t

• Bexarotene G protein coupled receptors GPCRs constitute a la

  2022-06-02

  

  G-protein coupled receptors (GPCRs) constitute a large family of 7 trans-membrane-spanning proteins that activate internal signal transduction cascades through binding to different ligands including neurotransmitters, peptides, and lipids [7]. This family of receptors has therapeutic potentials in t

• br Experimental br Acknowledgments The authors

  2022-06-02

  

  Experimental Acknowledgments The authors are grateful to Fundamental Scientific Research Fund of Chinese Academy of Medical Sciences (No. 2016ZX350030) for financial support. Introduction 2-Lysophosphatidylcholines (1-acyl-glycero-3-phosphocholines, 2-LPC) are blood derived factors involve

• br Conclusion The wild study reports seasonal variations in

  2022-06-02

  

  Conclusion The wild study reports seasonal variations in reproductive physiology, behavior and Poziotinib plasticity at different age stages in wild-caught Mongolian gerbils. The gerbils in breeding seasons have more mature sexual development, higher exploratory behavior, higher novelty preferen

• Sildenafil Citrate sale Results from the current study are n

  2022-06-02

  

  Results from the current study are not consistent with those of a previous study (Poock et al., 2015) where there was no differences in ovulation induction response when there was administration of gonadorelin hydrochloride and gonadorelin diacetate salts. These differences in results are likely due

• br Materials and methods br

  2022-06-01

  

  Materials and methods Results Discussion l-glutamate is the major excitatory neurotransmitter in the brain, and is functionally involved in many processes of the nervous system which have been connected with several neurological diseases [4]. These conditions are characterized by the time-d

• After ischemia expression of transcription factors including

  2022-06-01

  

  After ischemia, expression of transcription factors, including products of immediate early genes, stress proteins and neurotrophic factors are also altered in CA1 neurons78, 79. These proteins are potential candidates for downregulating of GluR2 expression by reducing mRNA transcription or stability

• There are two ways to transport

  2022-06-01

  

  There are two ways to transport FFAs into cells. First by passive diffusion. Second as the putative long-chain fatty Cyanine 5-dCTP transporters are proposed, CD36 the plasma membrane-associated fatty acid-binding protein (FABPpm) and fatty acid transport proteins (FATP) [11], where CD36 is responsi

• The presence of ghrelin s mRNA in the eye

  2022-06-01

  

  The presence of ghrelin's mRNA in the eye and the presence of ghrelin in the aqueous humor, along with a decrease of its levels in glaucoma, suggest a local role for this peptide in the ocular tissue [8], [16], [18]. There is no available data regarding the presence of GHSR-1 in the anterior segment

• br Central control of GI ghrelin secretion The CNS communica

  2022-06-01

  

  Central control of GI ghrelin secretion The CNS communicates with the GI tract through the vagus nerve originating in the DMV and sympathetic spinal afferents emanating from the thoracic spinal chord (Bray, 2000). The cells that secrete peripheral ghrelin are under direct control of these two pat

16269 records 454/1085 page Previous Next First page 上5页 451452453454455 下5页 Last page