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We further conducted stratified analyses
2023-08-29
We further conducted stratified analyses to observe changes in enzyme levels across the periods by subgroups. Fig. 1 shows the changes in GPx levels by subgroups of age, sex, and smoking status. In all participants, GPx levels decreased when air pollution levels declined but increased after the Olym
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br HMG proteins mobile modulators of
2023-08-29
HMG proteins: mobile modulators of chromatin structure and cellular phenotype The term “High Mobility Group” was originally coined for the HMG proteins because of their unusual solubility properties, their small size and their rapid mobility, relative to other chromatin proteins, during gel elect
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br Acknowledgments br Protein microarrays
2023-08-29
Acknowledgments Protein microarrays were developed to provide miniaturized high-throughput tools to study protein function, ML-291 and post-translational modifications. Just a few years ago, the seminal work performed in Stuart Schreiber's laboratory at Harvard University () and at Michael Sny
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For the derivatives a c another
2023-08-29
For the derivatives 3a–3c, another likely explanation for antifungal properties is that polymers bearing primary amine groups and secondary phosphoryl groups formed, enhancing complexation with the phosphate groups, and the complexes are amphiphilic (Palermo, Lee, Ramamoorthy, & Kuroda, 2011). The a
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br Conflicts of interest br Introduction When it comes to
2023-08-29
Conflicts of interest Introduction When it comes to risk taking, surgeons and anesthesiologists show greater risk taking than other physicians. Surgical procedures carry several risks of which infection is one. Surgical site infections (SSI) are the most common hospital acquired infection and
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Annexin V-Cy5 Apoptosis Kit Introduction Induction of long t
2023-08-29
Introduction Induction of long-term potentiation (LTP), the cellular correlate of learning and memory, triggers profound changes in the structure and function of excitatory synapses by increasing dendritic spine size and synaptic strength. Significant progress has been made in understanding the int
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br Guava tea leaves inhibit leukocyte type
2023-08-29
Guava tea leaves inhibit leukocyte-type 12-lipoxygenase activity Guava tea that is extracted from guava leaves contains a number of polyphenols, and is commonly taken as a dietary supplement. The extracts show a variety of beneficial effects such as antioxidative, anti-inflammatory and antiprolif
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br Materials and methods br
2023-08-29
Materials and methods Results and discussion First, we examined whether hypothalamic Akt-mediated signaling pathways are regulated postprandially in chickens. Refeeding significantly (P Edoxaban receptor concentrations significantly increased in chicks after 1 h of refeeding (958 ± 245% of 24
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When added to the culture
2023-08-28
When added to the culture medium, extracellular ATP is metabolized into adenosine by ectonucleotidases, and ARs are then activated by adenosine with concentrations in the micromolar range [27]. However, our study showed that activation of ARs by exogenous adenosine could not induce the odontoblastic
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In an effort to determine if one
2023-08-28
In an effort to determine if one 5ARI was more effective than the other, the Enlarged Prostate International Comparator Study (EPICS) [17] compared treatment with finasteride and dutasteride in 1630 men over the age of 50 and concluded that after one year of treatment, both groups had statistically
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A previous study reported that the serotonergic mechanism wa
2023-08-28
A previous study reported that the serotonergic mechanism was involved in the psychological stress-induced alteration in synaptic plasticity in the rat hippocampal CA1 field (Matsumoto et al., 2004). Sumitaka Inoue et al. (Inoue et al., 2014) reported that pretreatment with a 5-HT1A receptor partial
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An AXL decoy receptor with enhanced GAS binding properties M
2023-08-28
An AXL decoy receptor with enhanced GAS6-binding properties, MYD1, was engineered as a therapeutic tool to disrupt GAS6/AXL signaling in vivo (Kariolis et al., 2014). MYD1 was shown to block metastasis of human ovarian cancer retinoic acid receptor and a murine breast cancer cell line in grafting a
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br Acknowledgements We thank Dr Stefan Schulte
2023-08-28
Acknowledgements We thank Dr. Stefan Schulte-Merker and his group members at the Hubrecht Institute (Utrecht, the Netherlands) for their invaluable support of the zebrafish studies. Our work is supported by grants from the Dutch Cancer Society (KWF) and the Netherlands Organisation for Scientific
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br Diabetes and obesity fit or
2023-08-28
Diabetes and obesity: fit or fat; sugar or not: the autophagic verdict Type 2 diabetes and obesity are among the most emerging health problems worldwide. The factors that are responsible for the establishment of diabetes include decreased orexin production, rise in adiposity, and an increase in i
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br Activity and expression of aromatase in
2023-08-28
Activity and expression of aromatase in the hippocampus The brain, like the adrenals, gonads and the placenta, is a steroidogenic organ. This paradigm emerged from studies carried out as early as the 1980s by Baulieu and co-workers; these studies showed that steroids such as pregnenolone and dehy
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