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The review Bile acid receptor
2019-04-30
The review “Bile endothelin receptor receptor link nutrient sensing to metabolic regulation” by Li and Li is focused on bile acid receptors in the regulation of hepatic glucose and lipid metabolism and inflammation. Cholestasis and NAFLD are inflammatory liver diseases. Triglycerides are non-toxic,
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Contact mapping of an infarction by
2019-04-29
Contact mapping of an infarction by using NavX has been systematically validated in the left orthopox (LV) [3]. One advantage of the system is that it allows for simultaneous data collection from all electrodes of any or all catheters, if desired. Therefore, it is possible to allow for a quicker ac
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br Potential countermeasures for arrhythmias
2019-04-29
Potential countermeasures for arrhythmias during long-duration spaceflight A remote medical system will help to detect fatal arrhythmias in astronauts during the early stages. JAXA is in the process of developing a Remote Medical System [66]. This system consists of an electric stethoscope, pulse
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Results br Discussion br Conclusion
2019-04-29
Results Discussion Conclusion Conflict of interest Introduction Ablation on the mitral annulus is an important procedure for the non-pharmacological treatment of atrial fibrillation. However, it is known to cause injury of the left circumflex coronary artery (Lcx) [1,2]. In the present
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By inhibiting osteoclast activity one possible option relies
2019-04-29
By inhibiting osteoclast activity, one possible option relies to bisphosphonates, the synthetic analogs of pyrophosphate that induce osteoclast apoptosis, decrease osteoclast activation and function by inhibition of the mevalonate pathway [32]. Such therapeutic tools have been studied in primary bon
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There is also a pressing
2019-04-29
There is also a pressing need to change the way societal and dpp-iv inhibitors progress is measured to more accurately reflect an ecosocial approach to health. We are thus interested in applying the Happy Planet Index (HPI) at a community as well as at a national level. The HPI, an innovative measur
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What can be done to reduce
2019-04-29
What can be done to reduce morbidity and mortality in HEU infants? Notably, a third of all mortality in the Botswana trial occurred early, before randomisation. Similarly, in a trial of more than 14 110 infants in Zimbabwe, done in the pre-MTCT-prevention era, HIV-exposed uninfected infants had 50%
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To determine the discriminatory power
2019-04-28
To determine the discriminatory power of the ischiopubic index, the ROC curve was used (Fig. 3). The area under the curve for sex differentiation was 83.5% for the ischiopubic index. In the study population with a differentiation point of 100.47°, sensitivity of 82%, specificity of 78%, and accuracy
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Several studies have been performed by other groups that
2019-04-28
Several studies have been performed by other groups that indicate the possibility of discriminating renal cell carcinoma subtypes using texture analysis or single phase corticomedullary contrast-enhanced CT [18–21]. These studies also found that CT order ll-37 enhancement was a valid method of repre
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br Especificidades del Cono Sur de
2019-04-28
Especificidades del Cono Sur de América Latina Así como el suceso del Village marca un hito fundamental para la historia de las sexualidades disidentes norteamericanas, un evento particularmente importante ocurrido en 1942 en Argentina, “instaura una mácula que nuestros próceres se preocuparán, d
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br Conflict of interest br Authors contributions br
2019-04-28
Conflict of interest Authors\' contributions Introduction The introduction of risk-adapted intensified combination therapy has markedly improved outcomes for children with acute lymphoblastic leukemia (ALL). Unfortunately, disease recurrence and treatment-induced toxicity remain clinically
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The report contains no information about rotavirus serotypes
2019-04-28
The report contains no information about rotavirus serotypes in Rwanda. This is not that important though because for practical purposes surveillance of rotavirus serotypes is becoming obsolete as it has been convincingly shown that the efficacy and effectiveness of rotavirus vaccines against severe
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While the evidence linking Zika virus infection and
2019-04-28
While the evidence linking Zika virus infection and GBS in adults and separately between microcephaly and other neurological conditions in the fetuses of pregnant women is strong and growing, many key research and public health questions need to be addressed through comprehensive epidemiological stu
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In focal coronary spastic angina intravascular ultrasound wa
2019-04-28
In focal coronary spastic angina, intravascular ultrasound was reported to detect intima–media complex thickening and an increased sonolucent zone [16,17], and OCT can detect intimal thickening with low lipid and calcium deposits [18], which are believed to reflect neointimal hyperplasia subsequent
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br The follow up clinic These trial results have
2019-04-28
The follow-up clinic These trial results have significant implications for clinic efficiencies. The safe and effective replacement of the bulk of “routine” in-clinic evaluations demonstrated in TRUST (Fig. 3) has a huge implication for resource utilization. Although demanding adjustment to differ
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