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erk inhibitor br Community based bundled health intervention
2019-05-21
Community-based bundled health interventions are complex and challenging to implement, monitor, and assess in informal settlements (slums). Such settlements in urban areas are generally characterised by congestion, squalid conditions, deprivation, violence, crime, and poor sanitation. In Asia and
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Long QT syndrome LQTS a rare inheritable arrhythmia first
2019-05-20
Long QT syndrome (LQTS), a rare inheritable arrhythmia first described by Romano and Ward et al. in the 1960s, is characterized by the prolongation of the QT interval on surface ECGs and an increased risk of potentially fatal ventricular arrhythmias, especially torsade de pointes . In 1995, after ye
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A year old man was hospitalized following a
2019-05-20
A 36-year-old man was hospitalized following a first syncope attack while awake at night. No history of sudden death was reported in his family. On arrival, his consciousness was clear and his vital signs were stable. An electrocardiogram (ECG) showed sinus rhythm with ST-segment elevations and J wa
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Cisplatin based chemotherapy is commonly used in adjuvant CC
2019-05-20
Cisplatin-based chemotherapy is commonly used in adjuvant CCRT, but data on carboplatin-based chemotherapy with radiotherapy is lacking. Khoury et al reported that patients treated with carboplatin-based chemoradiotherapy show worse outcomes. However, the impact on patient comorbidities was not repo
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br Material and methods br Results br Discussion
2019-05-20
Material and methods Results Discussion PV isolation is currently the cornerstone for treatment of patients with paroxysmal AF [6]. An extended technique is circumferential PV isolation using point-by-point ablation around the PV ostium. However, that is a technically challenging and time-c
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A meta analysis of seven observational studies comparing dab
2019-05-20
A meta-analysis of seven observational studies, comparing dabigatran with warfarin, indicated that the ability of dabigatran to prevent ischemic stroke and bleeding outcomes is comparable to that of warfarin, which is consistent with the data obtained from the RE-LY trial [9]. These findings do not
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Fashions are dangerous things But it seems that global
2019-05-20
Fashions are dangerous things. But it bosentan seems that global health is no ephemeral trend. Every year, the field grows stronger. The Consortium of Universities for Global Health (CUGH) is a young organisation—its 2014 conference is only its fifth annual meeting. But in this short time, CUGH has
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Second the intervention was delivered by
2019-05-20
Second, the intervention was delivered by urotensin ii volunteers and administered through a local non-governmental organisation (NGO) that was committed to ongoing community involvement. Intervention success is dependent on quality. In this Ugandan trial, quality was enhanced by the reputation, ma
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Lo que Jos Enrique Rod teoriz en
2019-05-20
Lo que José Enrique Rodó teorizó en Ariel, Vasconcelos, de niño en la escuela de Eagle Pass, pareció vivirlo en carne propia. En esta pelea “escuelera”, asociemos, ¿se asumía Vasconcelos secreted frizzled related protein sí mismo como un Ariel, mientras a Jim, el gringo sanguíneo, lo consideraba co
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Independientemente del estado de nimo de los agentes del gob
2019-05-20
Independientemente del estado de ánimo de los agentes del gobierno colonial, ante el fin de la ocupación militar, La Lucha presentaba el advenimiento de la República de Cuba como un hecho con claroscuros para diferentes sectores de la sociedad cubana; por un lado, se anhelaba la salida del gobierno
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The lack of a single identified correlate of protection
2019-05-20
The lack of a single identified correlate of protection for LAIV should not deter future immunogenicity studies in resource-limited settings, especially using systems vaccinology approaches designed to dissect the complex interplay of innate and adaptive pathways following vaccination. John C Victor
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In our clinic the intracardiac electrogram
2019-05-20
In our clinic, the intracardiac electrogram recorded by the ICD showed repetitive non-reentrant ventriculoatrial synchrony (RNRVAS), which was associated with hypotension and chest discomfort (Fig. 1). We suspected that the RNRVAS caused the hypotension; therefore, we performed electrophysiologic an
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Para concluir plantear a que todo esfuerzo
2019-05-20
Para concluir, plantearía que todo esfuerzo por alcanzar la paz en cada una de estas tres etapas sería infructuoso si no se educa para la paz y para el posconflicto, educación que debe recibir toda sociedad civil para entender y afrontar los cambios futuros del país en todo orden, incluyendo los niv
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Benjam n Arditi por su
2019-05-20
Benjamín Arditi, por su parte, ha desarrollado parte de su obra en diálogo con y contra Laclau. En lo que nos ocupa, en una extensa reseña de La razón populista, Arditi repara en la triple sinonimia de populismo, hegemonía y política y, además, lanza un conjunto de observaciones agudas. Al igual que
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br Conformational control inhibition Conformational escape r
2019-05-20
Conformational control inhibition Conformational escape resistance is a phenomenon where point mutations (such as T315I) drive the Abl kinase toward the active type I state. “Switch-control inhibitors” bind in a non-ATP-competitive fashion to residues (E282, R386) the Abl protein uses to switch b
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