• En esta columna al mismo tiempo que se congratulaban de

  2019-04-20

  

  En esta columna, al mismo tiempo que se congratulaban de informar la generosa donación de Andrew Carnegie, de 250 mil dólares para una biblioteca en La Habana, señalaban la inexorable presencia del poder foráneo estadounidense. Una vez inaugurada la República, afirmaba La Lucha: “Después del 20 de m

• Despite taking hydroxyurea for months his leukocytosis splen

  2019-04-20

  

  Despite taking hydroxyurea for 6 months, his leukocytosis, splenomegaly, and constitutional symptoms were poorly controlled and his performance status and overall function had declined even further. There was little clinical benefit to gain by increasing the hydroxyurea dose further especially in th

• FPET is a valuable tool to support monitoring of SDG

  2019-04-20

  

  FPET is a valuable tool to support monitoring of SDG 3·7, which calls for universal access to family planning by 2030, albeit with a focus on demand and utilisation rather than access. Nonetheless, subnational geographic projections must be considered in light of some data limitations. Unmarried wom

• br CONCLUSI N La escritura

  2019-04-19

  

  CONCLUSIÓN La escritura histórica, referente n-acetyl-l-cysteine los años de guerra en Guatemala, continúa permeada por un debate que se incrustó en la sociedad guatemalteca, es decir, la dicotomía: comunismo versus anticomunismo, que proyectó el mundo polarizado de la Guerra Fría. La relevancia

• br Introduction Human endogenous retroviruses HERVs are

  2019-04-19

  

  Introduction Human endogenous retroviruses (HERVs) are genetic remnants of ancient retroviral infections of the germ line produced during primate evolution which are now transmitted vertically. To date, approximately 8% of the human genome is composed of such retroviral sequences [1]. Most HERVs

• In summary Welch and colleagues review is important Not

  2019-04-19

  

  In summary, Welch and colleagues\' review is important. Not all systematic reviews on the same topic reach the same conclusion, but the convergence between the Campbell and Cochrane reviews here could hardly be stronger. The additional network and subgroup analyses in the Campbell review find no evi

• Cell adhesion to extracellular matrix requires

  2019-04-19

  

  Cell adhesion to extracellular matrix requires the interaction of different molecules like selectins, cadherins and integrins [21]. Especially αvβ3 integrin has been proposed to mediate the adhesion of malignant cells in different entities such as multiple myeloma and breast cancer [22,23]. Upon exp

• br Introduction Atrial fibrillation AF is the

  2019-04-19

  

  Introduction Atrial fibrillation (AF) is the most clinically prevalent tachyarrhythmia [1,2]. AF is a potential risk factor for stroke, and AF-associated strokes are often severe, resulting in disability or death [3–6]. Anticoagulant therapy with the vitamin K antagonist warfarin reduces the risk

• Feeding stimulates gallbladder contraction emptying its cont

  2019-04-19

  

  Feeding stimulates gallbladder contraction, emptying its contents into the upper part of the small intestine, where CBAs activate pancreatic lipase to release monoglycerides and free fatty acids from triglycerides. Mixed micelles with monoglycerides, fatty acids, cholesterol, and fat-soluble vitamin

• Some health related topics are guaranteed to stir up heated

  2019-04-19

  

  Some health-related topics are guaranteed to stir up heated debate in the general public whenever they purchase AICAR crop up in the news. Publishing a research paper on chronic fatigue syndrome, homoeopathy, or mode of childbirth is a recipe for a media field day, a lively letters section, and a ja

• Ya se alamos l neas arriba que el elogio

  2019-04-18

  

  Ya señalamos líneas arriba que el elogio respondía gpcr signaling pathway una tradición primordialmente masculina. Ese rasgo se reproduce, claro está, en la RF, lo cual se explica fácilmente por las redes de sociabilidad que nutrían a esta revista y que esbozamos al principio de este artículo. La ún

• However days after he completed the last chemotherapy round

  2019-04-18

  

  However, 10 days after he completed the last chemotherapy round with etoposide, the patient again visited our emergency department manifesting a fever. Lab data reported leukopenia, anemia, and elevated LDH (leukocyte:3600/μL, hemoglobin:10.9 g/dL, platelet:168 × 103/μL, and LDH:498 U/L). Thereafter

• Introduction Multiple myeloma MM is the

  2019-04-18

  

  Introduction Multiple myeloma (MM) is the most frequent cancer to involve the skeleton with 80–90% of patients developing bone lesions during their disease course [1]. Myeloma bone lesions are purely osteolytic and are associated with severe and debilitating bone pain, pathologic fractures, hyperca

• Extensive vascularization of the skeletal tissue suggests th

  2019-04-18

  

  Extensive vascularization of the skeletal tissue suggests the importance of blood vessels in regulating its physiological functions. Endothelium, the innermost cellular layer of blood vessels forms a central component of the bone marrow vascular microenvironment [7]. Recent evidence support that a p

• Roughly years have gone by since the identification of the

  2019-04-18

  

  Roughly 15 years have gone by since the identification of the main characters involved in the interplay of the RANK–RANKL system. This gave rise to the race for elucidating their biological role . In those years, in vivo silencing experiments for both Receptor Activator of Nuclear Factor κ B (RANK)

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